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Faculty Publications

Moien Kanaan, PH.D.
Associate Professor

Hereditary Research Laboratory - Life science Department

.

Contact Address:

Bethlehem University
Freres Street
P.O.Box 9
Bethlehem
Palestine
E-Mail: mkanaan@bethlehem.edu


PUBLICATIONS

  • Olson GB. Kanaan MN . Kelly LM, Jones JF. (1987) Correlation between allergy and persistent Epstein-Barr virus infection in chronic-active Epstein-Barr virus-infected patients, J Allergy Clin Immunol 78: 308-314. Olson GB, Kanaan MN , Kelly LM, Jones JF. (1988) Specific allargen-induced Epstein-Barr nuclear antigen-positive B-cells from patients with chronic-active Epstein-Barr virus nuclear antigen-positive B-cells from patients with chronic-active Epstein-Barr virus infections. J. Allergy Clin Immunol 78: 315-320.


  • Kanaan MN , Marzluf GA. (1991) Mutational analysis of the DNA binding domain of the CYS-3 regulatory gene. Mol Cell Biol 11: 4356-4359.


  • Kanaan MN , Marzuluf GA (1992) The DNA binding domain of the CYS3 regulatory gene is bipartite. J Biochem 31: 3197-3203.


  • Kanaan MN , Marzulf GA (1993) The positive acting regulatory protein CYC3: Nuclear localization, autogenous control and regions required for transcriptional activation. Mol Gen Genet 239: 334-344.


  • Muller F, Kruger D, Sattelgger E, Hoffmann B, Wende A, Ballario P, Kanaan M, Barthelmess IB (1995). Cpc-2, a gene encoding a highly conserved protein with a repetitive segmental structure involved in general amino acid control and female fertility. Mol Gen Genet. 248: 162-173.


  • Marzluf GA , Kanaan MN . (1995) Molecular analysis of DNA-binding, trans-acting regulatory proteins. Bethlehem J 14: 21 -33.


  • Kanaan MN (1996) Can we control MRSA-strains in hospitals in Palestine ? Bethlehem J 15: 106-113.


  • Kanaan MN . (1997) Molecular strategies for typing and properties of epidemic methicillin-resistant Staphylococcus aureus. J Hos Infec 15: 12-17.


  • Kanaan MN . (1999) High concordance between quantitative antibiogram and pulse field macrorestriction analysis in typing methicillin-resistant Staphylococcus aureus. Epidemioloy 23:145-148


  • Kanaan MN , Shaen H, Morrow J, Sobe T, King M-C, Avraham KB, Lynch ED. (1999) Genetic analysis of hearing loss in Palestinian kindreds. Amer Soc Human Genet, Abstract.


  • Sobe T, Vreugde S, Shahin H, Berlin M, Kanaan M, Yaron Y, Orr-Urtreger A, Frydman M, Shohat M, Avraham KB (2000) . Prevalence and expression of inherited connexin 26 mutations associated with nonsyndromic hearing loss in the Israeli population, Human Genetic:106,50-57.


  • Hashem Shahin, Tom Walsh, Tama Sobe, Eric Lynch, Mary-Claire King, Karen B. Avraham , , Moien Kanaan (2002) Genetics of congenital deafness in the Palestinian population: Multiple connexin 26 alleles with shared origins in the Middle East . Hum.Genet.110:284-289


  • Abd El-latif, M ,Filon D, Oppenheim A, Kanaan M (2002) . IVS1-6 accounts for half of the thalassemia chromosomes in the Palestinian population of the mountain region. Hemoglobin . 26 ,1:33-40


  • Aoi Nakano, Gilles G. Lestringant, Tamar Paperna, Reuven Bergman, Ruth Gershoni, Philippe Frossard, Moien Kanaan , Guerrino Meneguzzi, Gabriele Richard, Ellen Pfendner, Jouni Uitto, Leena Pulkkinen, Eli Sprecher  (2002) Junctional epidermolysis bullosa in the Middle East :clinical and genetic studies in a series of consanguinous families. J.Am.Acad.Dermatol :46,4, 510-5


  • Ingrid Zwaenepoel, Mirna Mustapha, Michel Leibovici, Elisabeth Verpy, Richard Goodyear, Xue Zhong Liu, Sylvie Nouaille, Walter E. Nance, Moien Kanaan , Fredj Tekaia, Jacques Loiselet, Jean Weissenbach, Marc Lathrop, Guy Richardson and Christine Petit (2002) Otoancorin, an inner ear protein restricted to the interface between the apical surface of sensory epithelia and their overlying acellular gels, is defective in autosomal recessive deafness DFNB22.PNAS:99,9,6240-6245.


  • Tom Walsh, Vanessa Walsh, Sara Vreugde, Ronna Hertzano, Hashem Shahin, samnder Haika, Ming K.Lee, Moien Kanaan , Mary-Claire King and Karen Avraham. (2002) . From flies to our ears: mutations in a human class 111 myosin cause progressive nonsyndromic hearing loss DFNB30. PNAS:99,7518-7523.


  • Novel PDGF_R antisense encapsulated in polymeric nanospheres for the treatment of restenosis .(2002) H Cohen-Sacks, Y Najajreh,, V Tchaikovski, G Gao, V Elazer, R Dahan, I Gati, M Kanaan , J Waltenberger3 and G Golomb. Gene Therapy :9, 30-39


  • Green GE, Mueller RF, Cohn ES, Avraham KB, Kanaan M , Smith RJH (2003) .Audiological manifestations and features of Connexin 26 deafness. Audiolog Med:1:5-11.


  • Moien kanaan and Hashem Shahin. (2003) . Guidelines for Palestinian Families with Hearing Loss Affected Kids , Bethlehem University Publication.


  • Epidermolysis bullosa simplex in Israel : clinical and genetic features (2003) . Ciubutaro D, Bergman R, Baty D, Indelman M, Pfender E, Petronius D, Moualem H , Kanaan M , Ben Amitai D, McLean WHI, Uitto J, Sprecher E J, Arch Dermato:139,498-505


  • Lionel F. Schnur,* Abdelmageed Nasereddin,* Carol L. Eisenberger, Charles L. Jaffe, Mustafa El Fari, Kifaya Azmi, Gerlind Anders, Mireille Killick-Kendrick, Robert Killick-Kendrick, Jean-Pierre Dedet, Francine Pratlong, Moien Kanaan , Tamar Grossman, Raymond L. Jacobson, Gabrielle Schonian, And Alon Warburg (2004 ) Multifarious Characterization Of Leishmania Tropica From A Judean Desert Focus, Exposing Intraspecific Diversity And Incriminating Phlebotomus Sergenti As Its Vector, Am. J. Trop. Med. Hyg., 70(4), pp. 364–372


  • Tom Walsh, Amal Abu Rayan, Hashem Shahin , , Karen B. Avraham, Mary-Claire King and Moien Kanaan . (2004). A founder mutation of TMPRSS3 associated with nonsyndromic sensorineural congenital deafness in the Palestinian population, submitted

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